Happy toddler smiles at home

Josiah is a lucky little boy who will soon have a kidney transplant to further treat his renal failure. His parents believe Dr. Timothy Crombleholme and Connecticut Children are miracles in their lives. Read his full story below. 

Fetal renal failure (FRF) is a clinical syndrome that has several distinct causes but results in the inability to produce sufficient urine to maintain normal amniotic fluid volume, which is essential for normal fetal lung development. In FRF, the lack of amniotic fluid limits lung development and causes pulmonary hypoplasia, a life-threatening condition where the baby is unable to breathe on their own after birth.

Additional Resources:

Beyond Fetal Renal Failure: Josiah’s Story

Three Things to Know about Treating Fetal Renal Failure

Deciding to Treat Fetal Renal Failure: Information & Support for Families

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